Efficacy and tolerability of BP-C1 in metastatic breast cancer: a Phase II, randomized, double-blind, and placebo-controlled Thai multi-center study

Kritiya Butthongkomvong, Nilubol Raunroadroong, Sirikul Sorrarichingchai, Isaraporn Sangsaikae, Vichien Srimuninnimit, Henrik Harling, Stig Larsen                                                  Breast Cancer – Targets and Therapy 2019:11 43–51

Effect of the polyphenol composition BP‑C3 on haematological and intestinal indicators of 5‑fluorouracil toxicity in mice

Andrey V. Panchenko, Elena I. Fedoros, Sergey E. Pigarev, Mikhail A. Maydin, Ekaterina A. Gubareva, Maria N. Yurova, Galina S. Kireeva, Galina P. Lanskikh, Margarita l. Tyndyk and Vladimir N. Anisimov
International Journal of Radiation Biology: https://doi.org/10.1080/09553002.2018.1416204

Radioprotective and radiomitigative effects of BP-C2, a novel lignin-derived polyphenolic composition with ammonium molybdate, in two mouse strains exposed to total body irradiation

Vladimir N. Bykov, Igor S. Drachev, Sergey Yu. Kraev, Mikhail A. Maydin, Ekaterina A. Gubareva, Sergey E. Pigarev, Vladimir N. Anisimov, Irina A. Baldueva, Elena I. Fedoros, and Andrey V. Panchenko
Experimental and Therapeutic Medicine 15: 3124-3132, 2018

Benzene-Poly-Carboxylic Acids Complex with Cis-Diammineplatinum (II) Dichloride in the Treatment of Stage IV Breast Cancer Patients

Sagita Dewi, Stig Larsen, Vichien Srimuninnimit, Yen-Shen Lu, Tjakra Manuaba, Steen Lindkaer-Jensen
The Open Breast Cancer Journal, 2013, 5, 7-15.

BP-C1 in the treatment of patients with stage IV breast cancer: a randomized, double-blind, placebo-controlled multicenter study and an additional open-label treatment phase

Larsen S, Butthongkomvong K, Manikhas A, Trishkina E, Poddubuskaya E, Matrosova M, Srimuninnimit V, Lindkær-Jensen S.
Breast Cancer: targets and Therapy 2014:6 179-189.

The hormone receptors status influences the effect of BP-C1 in treatment of stage IV metastatic breast cancer: a randomized, double blind and placebo controlled multicenter study

Butthongkomvong K, RaunroadroongN, Sorrarichingchai S, Sangsaikae I, Srimuninnimit V, Harling H and Larsen S
(In press. Breast Cancer: targets and Therapy).

Positive effects on hematological and biochemical imbalances in patients with metastatic breast cancer stage IV, of BP-C1, a new anticancer substance

Lindkær-Jensen S, Larsen S, Habib-Lindkær-Jensen N, Fagertun HE.
Drug Design, Development and Therapy 2015:9 1481-1490.

Cis-diammineplatinum II dichloride benzene-polycarboxylic-and complex (BP-C1) in long-term treatment of two Stage IV Metastatic Breast Cancer patients

Poddubuskaya E, Butthongkomvong K and Larsen S􀍵
(In manuscript)

Results and prospects of development of new polyphenolic drugs for cancer patients

Anisimov VN,  Larsen S, Lofberg S, Baldueva IA, Malek AV, Kirkegaard Nielsen T, Fedoros E, Perminova IV, Drobyshev EY,  Bykov VN,  Panchenko AV, Scherbakov AM and Belyaev AM
Oncotarget, 2017, Vol 8 (59), pp:100921-100956

Tolerability and pharmacokinetic profile of a novel benzene-poly-carboxylic acids complex with cis-diammine-platinum (II) dichloride in dogs with malignant mammary tumours

Veronica. Kristiansen, S. Dewi, T. E. Horsberg,  T. J. Jonasdottir, L. Moe, B. Berlinger, S. Lindkær-Jensen and S. Larsen.
Veterinary and Comparative Oncology, 2015, DOI: 10.1111/vco. 12144.

Benzene-Poly-Carboxylic Acid Complex, a Novel Anti-Cancer Agent Induces Apoptosis in Human Breast Cancer Cells

Fuad Fares, Naiel Azzam, Fares, Stig Larsen, Steen Lindkaer-Jensen
PLOS ONE, 2014 February, 9(2), e85156

Anticancer activity and tissue distribution of platinum (II) complex with lignin-derived polymer of benzene-poly-carboxylic acids,

Solovyev ND, Fedoros EI, Drobyshev E,  Ivanenko NB, Pigarev SE, Tyndyk ML,  Anisimov VN,  Vilpan YA, And Panchenko AV
Journal of Trace Elements in Medicine and Biology, 2017 September, 43, 72-79.

Using human cancer cell lines as in vitro model for testing the efficacy of CDBPA; A new anticancer drug

Fares  F, Jensen CL, Larsen S,  Azzam N, Fares B and indkær-Jensen S.
Journal of Tissue Science & Engineering, 2016, 7:2, 1000168.

An Innovative Cis-Diammineplatinum (II) Benzene-Polycarboxylic-Acids Complex Inhibits Growth of Burkitt’s Cell Lymphoma In Vitro and In Vivo

Steen Lindkær-Jensen, Claus L. Jensen, Naiel Azzam, Rinat Bar-Shalom, Basem Fares, Nina Habib, Stig Larsen and Fuad Fares
Journal of Hematology & Thromboembolic Diseases 2016, 4:1, 1000234.

Novel water-soluble lignin derivative BP-Cx-1: identification of components and screening of potential targets in silico and in vitro

Fedoros EI1,2, Orlov AA3, Zherebker A3,4, Gubareva EA1, Maydin MA1, Konstantinov AI3, Krasnov KA5, Karapetian RN6, Izotova EI2, Pigarev SE2, Panchenko AV1, Tyndyk ML1, Osolodkin DI7,8, Nikolaev EN4,9,10, Perminova IV3, Anisimov VN1
Oncotarget, 2018 April 6, 9(26),18578-18593

An Innovative Complex of Benzene-Poly-Carboxylic Acid and Molybdenum, for Prevention and Treatment of Radiation Dermatitis

Fuad Fares, Basem Fares, Naiel Azzam, Munir Nashashibi, Alex Nevelsky, Stig Larsen and Steen Lindkær-Jensen
Medicinal chemistry, 2015, 5:10, 447-451.

BP-C2 improves Functional status, Quality of Life and Corrects Biochemical Imbalances as Adjuvant Therapy to FOLFIRINOX Treatment:  A Case of Advanced Inoperable Pancreatic Cancer

Ibrahim T, Larsen S, Lindkær Jensen  NH, Lindkær-Jensen S
Journal of Clinical Case Reports, 2015, 5:4, 1000514.

Polyphenolic drug composition based on benzenepolycarboxylic acids (BP-C3) increases life span and inhibits spontaneous tumorigenesis in female SHR mice, Anisimov VN1, Popovich IG1, Zabezhinski MA1, Yurova MN1, Tyndyk ML1, Anikin IV1, Egormin PA1, Baldueva IA1, Fedoros EI1,2, Pigarev SE1,2, Panchenko AV1

AGING Journal, 2016, 8(9), 1866-1875.

Pharmacokinetics and tissue distribution of novel platinum containing anticancer agent BP-C1 studied in rabbits using sector field inductively coupled plasma mass spectrometry

Navolotskii DV, Ivanenko NB, Solovyev ND, Fedoros EI, Panchenko AV
Drug Test Anal. 2015 Sep;7(9):737-44. doi: 10.1002/dta.1824.