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BP-C1 Oncology


BP-C1 is a unique product that clinically has proven to have both strong palliation properties as well as tumor control properties. .....read more

BP-C2 Radiation Defence


BP-C2 incorporates immunomodulating and chelating ligand and a molybdenum, needed for detoxification. .....read more

BP-C1 Oncology


BP-C1 is a unique product that clinically has proven to have both strong palliation properties as well as tumor control properties. .....read more

Scientific Publications

This section contains a select list of scientific publications on drug candidates in Meabco’s pipeline.

 

Radioprotective and radiomitigative effects of BP-C2, a novel lignin-derived polyphenolic composition with ammonium molybdate, in two mouse strains exposed to total body irradiation

Vladimir N. Bykov,Igor S. Drachev,Sergey Yu. Kraev,Mikhail A. Maydin,Ekaterina A. Gubareva,Sergey E. Pigarev,Vladimir N. Anisimov,Irina A. Baldueva,Elena I. Fedoros &Andrey V. Panchenko

Published online: 21 Dec 2017

https://doi.org/10.1080/09553002.2018.1416204

 
An Innovative Cis-Diammineplatinum (II) Benzene-Polycarboxylic-Acids Complex Inhibits Growth of Burkitt`s Cell Lymphoma In Vitro and In Vivo

Steen Lindkær-Jensen, Claus L. Jensen, Naiel Azzam, Rinat Bar-Shalom, Basem Fares, Nina Habib, Stig Larsen and Fuad Fares

Published Date: February 28, 2016

Journal of Hematology & Thromboembolic Diseases

dx.doi.org/10.4172/2329-8790.1000234

 

BP-C2 improves Functional status, Quality of Life and Corrects Biochemical Imbalances as Adjuvant Therapy to FOLFIRINOX Treatment:  A Case of Advanced Inoperable Pancreatic Cancer.

Ibrahim T, Larsen S, Lindkær Jensen NH, Lindkær-Jensen S. 

J Clin Case Rep 2015; 5: 514. doi:10.4172/2165-7920.1000514

https://www.researchgate.net

Pharmacokinetics and tissue distribution of novel platinum containing anticancer agent BP-C1 studied in rabbits using sector field inductively coupled plasma mass spectrometry.

Navolotskii DV, Ivanenko NB, Solovyev ND, Fedoros EI, Panchenko AV.

Drug Test Anal. 2015 Sep;7(9):737-44. doi: 10.1002/dta.1824.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744679/


An Innovative Complex of Benzene-Poly-Carboxylic Acid and Molybdenum, for Prevention and Treatment of Radiation Dermatitis

Fuad Fares, Basem Fares, Naiel Azzam, Munir Nashashibi, Alex Nevelsky, Stig Larsen and Steen Lindkær-Jensen

http://www.omicsonline.org/pdfdownload.php?download=open-access/an-innovative-complex-of-benzenepolycarboxylic-acid-andmolybdenum-for-prevention-and-treatment-of-radiation-dermatitis-2161-0444-1000299.pdf

 

Positive effects on hematological and biochemical imbalances in patients with metastatic breast cancer stage IV, of BP-C1, a new anticancer substance.

Lindkær-Jensen S, Larsen S, Habib-Lindkær-Jensen N, Fagertun HE

Published Date: 13 March 2015

http://www.dovepress.com/positive-effects-on-hematological-and-biochemical-imbalances-in-patien-peer-reviewed-article-DDDT#

 

BP-C1 in the treatment of patients with stage IV breast cancer: a randomized, double-blind, placebo-controlled multicenter study and an additional open-label treatment phase

Larsen S, Butthongkomvong K, Manikhas A, Trishkina E, Poddubuskaya E, Matrosova M, Srimuninnimit V, Lindkær-Jensen S

Published Date November 2014 Volume 2014:6 Pages 179—189

http://dx.doi.org/10.2147/BCTT.S71781

 

Benzene-Poly-Carboxylic Acid Complex, a Novel Anti-Cancer Agent Induces Apoptosis in Human Breast Cancer Cells

Fuad Fares, Naiel Azzam, Fares, Stig Larsen, Steen Lindkaer-Jensen

Published: February 11, 2014, DOI: 10.1371/journal.pone.0085156

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0085156 


Quality of life, efficacy and tolerability of long term treatment with BP-C1, in patients with stage IV breast cancer

Stig Larsen, S. Lindkaer-Jensen

EACR23-EJC, 2014, European Journal of Cancer

Page 286, s201,829

http://www.ejcancer.com/article/S0959-8049(14)50732-0/abstract

 

Between- and within-patient n-level response surface pathway design in dose-finding studies

Sagita Dewi, Veronica Kristiansen, Steen Lindkaer-Jensen, Stig Larsen

Published Date July 2014 Volume 2014:6 Pages 63—74

http://dx.doi.org/10.2147/OAJCT.S57955 

 

Benzene-Poly-Carboxylic Acids Complex with Cis-Diammineplatinum (II) Dichloride in the Treatment of Stage IV Breast Cancer Patients

Sagita Dewi, Stig Larsen, Vichien Srimuninnimit, Yen-Shen Lu, Tjakra Manuaba, Steen Lindkaer-Jensen

The Open Breast Cancer Journal, 2013, 5, 7-15
http://benthamopen.com/ABSTRACT/TOBCANJ-5-7

 

Tolerability and pharmacokinetic profile of a novel benzene-poly-carboxylic acids complex with cis-diammineplatinum (II) dichloride in dogs with malignant mammary tumours

Veronica. Kristiansen, S. Dewi, T. E. Horsberg,  T. J. Jonasdottir, L. Moe, B. Berlinger, S. Lindkær-Jensen and S. Larsen
Veterinary and Comparative Oncology
http://onlinelibrary.wiley.com/doi/10.1111/vco.12144/full


MEABCO A/S  |  Richard Mortensens Vej 61  |  DK-2300 Copenhagen  |  Telephone: +45 32 46 03 70  | e-mail: info@meabco.com
2017
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